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Peptide record

TPDB49061

Antifungal standard
57 amino acids
Basic Information
3D PDB MODEL
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TPDB49061
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 57-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
LISDKCTEGCKSTIGCNTRCMMRGGGYCESAKIHGAVKIFCCCNNYSNSPISSPVIN
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C250H408N74O81S10
QW
C
6067.04
8.10
7
3
16
+3
1.30
-0.040
61.58
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
3480
0.57
25
Residue Composition
number
2
A
2
R
5
N
1
D
8
C
2
E
0
Q
6
G
1
H
6
I
1
L
4
K
2
M
1
F
2
P
7
S
3
T
0
W
2
Y
2
V
Amino Acid Distribution
A: 2 R: 2 N: 5 D: 1 C: 8 E: 2 Q: 0 G: 6 H: 1 I: 6 L: 1 K: 4 M: 2 F: 1 P: 2 S: 7 T: 3 W: 0 Y: 2 V: 2
Chemical Descriptors
57 reviewed residue count
C250H408N74O81S10 sequence-only estimate (linear, free termini)
6067.04 sequence-only estimate (linear, free termini)
8.10 sequence-only estimate (linear, free termini)
+3 sequence-only estimate (linear, free termini)
1.30 sequence-only estimate (linear, free termini)
-0.040 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.