TPDB

3D PDB MODEL

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TPDB ID TPDB49061

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 57-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

LISDKCTEGCKSTIGCNTRCMMRGGGYCESAKIHGAVKIFCCCNNYSNSPISSPVIN

FASTA

>TPDB49061|Antifungal|length=57
LISDKCTEGCKSTIGCNTRCMMRGGGYCESAKIHGAVKIFCCCNNYSNSPISSPVIN

Formula C250H408N74O81S10

Absent Amino Acids QW

Common Amino Acids C

Mass 6067.04

PI 8.10

Basic Residues 7

Acidic Residues 3

Hydrophobic Residues 16

Net Charge +3

Boman Index 8.19

Hydrophobicity -0.040

Aliphatic Index 61.58

Half Life

Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min

Extinction Coefficient Cystines 3480

Absorbance 280nm 57.36

Polar Residues 25

number

2

A

2

R

5

N

1

D

8

C

2

E

0

Q

6

G

1

H

6

I

1

L

4

K

2

M

1

F

2

P

7

S

3

T

0

W

2

Y

2

V

Amino Acid Distribution

A: 2 R: 2 N: 5 D: 1 C: 8 E: 2 Q: 0 G: 6 H: 1 I: 6 L: 1 K: 4 M: 2 F: 1 P: 2 S: 7 T: 3 W: 0 Y: 2 V: 2

Length

57

Formula

C250H408N74O81S10

Mass

6067.04

PI

8.10

Net Charge

+3

Boman Index

8.19

Hydrophobicity

-0.040

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.