TPDB

3D PDB MODEL

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TPDB ID TPDB49060

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 70-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

GAPPQDCWNLVTFPAKCGIHGKKKCFKEMESKYQQRFLQCTCKNLKPEPKSPKDEHDCTCQRANPYECNS

FASTA

>TPDB49060|Antifungal|length=70
GAPPQDCWNLVTFPAKCGIHGKKKCFKEMESKYQQRFLQCTCKNLKPEPKSPKDEHDCTCQRANPYECNS

Formula C347H540N100O104S9

Absent Amino Acids

Common Amino Acids K

Mass 8065.25

PI 8.30

Basic Residues 14

Acidic Residues 8

Hydrophobic Residues 15

Net Charge +4

Boman Index 24.10

Hydrophobicity -1.121

Aliphatic Index 30.71

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 8980

Absorbance 280nm 111.34

Polar Residues 25

number

3

A

2

R

4

N

3

D

8

C

5

E

5

Q

3

G

2

H

1

I

3

L

10

K

1

M

3

F

7

P

3

S

3

T

1

W

2

Y

1

V

Amino Acid Distribution

A: 3 R: 2 N: 4 D: 3 C: 8 E: 5 Q: 5 G: 3 H: 2 I: 1 L: 3 K: 10 M: 1 F: 3 P: 7 S: 3 T: 3 W: 1 Y: 2 V: 1

Length

70

Formula

C347H540N100O104S9

Mass

8065.25

PI

8.30

Net Charge

+4

Boman Index

24.10

Hydrophobicity

-1.121

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.