Peptide record

TPDB49059

Antifungal standard
45 amino acids
Basic Information
3D PDB MODEL
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TPDB49059
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 45-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
RLCRVRGTRGHCFNDHGCDKVCTREGFVRGKCNGILRRCICDRQC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C209H351N81O59S8
AMPSWY
R
5199.07
9.06
13
4
9
+7
3.51
-0.627
54.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
500
0.10
13
Residue Composition
number
0
A
9
R
2
N
3
D
8
C
1
E
1
Q
6
G
2
H
2
I
2
L
2
K
0
M
2
F
0
P
0
S
2
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 9 N: 2 D: 3 C: 8 E: 1 Q: 1 G: 6 H: 2 I: 2 L: 2 K: 2 M: 0 F: 2 P: 0 S: 0 T: 2 W: 0 Y: 0 V: 3
Chemical Descriptors
45 reviewed residue count
C209H351N81O59S8 sequence-only estimate (linear, free termini)
5199.07 sequence-only estimate (linear, free termini)
9.06 sequence-only estimate (linear, free termini)
+7 sequence-only estimate (linear, free termini)
3.51 sequence-only estimate (linear, free termini)
-0.627 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.