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Peptide record

TPDB49058

Antifungal standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB49058
Antifungal
Anti-infective peptides
AFP-GFuse
standard
No
A 12-aa standard natural antifungal peptide sequence curated from AFP-GFuse, with an available 3D structural model.
Sequence
FIKWKFRWWKWR
Physicochemical Analysis
C98H131N25O13
ANDCEQGHLMPSTYV
W
1867.28
12.43
5
0
7
+5
-5.38
-1.183
32.50
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
22000
1178.19
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
0
L
3
K
0
M
2
F
0
P
0
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 0 K: 3 M: 0 F: 2 P: 0 S: 0 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
12
C98H131N25O13
1867.28
12.43
+5
-5.38
-1.183
Evidence Records 7 records
Evidence 1 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

Pseudomonas aeruginosa PAO1

Source & Reference

NA

Other

active against P. aeruginosa PAO1 (MIC 8 ug/ml), E. coli (MIC 4 ug/ml), S. typhimurium (MIC 8 ug/ml), S. aureus (MIC 4 ug/ml), S. epiderm
Evidence 2 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

Escherichia coli

Source & Reference

NA

Other

active against P. aeruginosa PAO1 (MIC 8 ug/ml), E. coli (MIC 4 ug/ml), S. typhimurium (MIC 8 ug/ml), S. aureus (MIC 4 ug/ml), S. epidermidis (MIC 2 ug/ml), E.
Evidence 3 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

S. typhimurium

Source & Reference

NA

Other

active against P. aeruginosa PAO1 (MIC 8 ug/ml), E. coli (MIC 4 ug/ml), S. typhimurium (MIC 8 ug/ml), S. aureus (MIC 4 ug/ml), S. epidermidis (MIC 2 ug/ml), E. faecalis ATCC29212 (MIC 8 ug/m
Evidence 4 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

Staphylococcus aureus

Source & Reference

NA

Other

st P. aeruginosa PAO1 (MIC 8 ug/ml), E. coli (MIC 4 ug/ml), S. typhimurium (MIC 8 ug/ml), S. aureus (MIC 4 ug/ml), S. epidermidis (MIC 2 ug/ml), E. faecalis ATCC29212 (MIC 8 ug/ml), and C. albicans (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
2 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

NA

Other

C 8 ug/ml), E. coli (MIC 4 ug/ml), S. typhimurium (MIC 8 ug/ml), S. aureus (MIC 4 ug/ml), S. epidermidis (MIC 2 ug/ml), E. faecalis ATCC29212 (MIC 8 ug/ml), and C. albicans (MIC 8 ug/ml). It is the most activ
Evidence 6 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

Enterococcus faecalis ATCC29212

Source & Reference

NA

Other

ml), S. typhimurium (MIC 8 ug/ml), S. aureus (MIC 4 ug/ml), S. epidermidis (MIC 2 ug/ml), E. faecalis ATCC29212 (MIC 8 ug/ml), and C. albicans (MIC 8 ug/ml). It is the most active one in this indolicidin variants.
Evidence 7 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

Candida albicans

Source & Reference

NA

Other

eus (MIC 4 ug/ml), S. epidermidis (MIC 2 ug/ml), E. faecalis ATCC29212 (MIC 8 ug/ml), and C. albicans (MIC 8 ug/ml). It is the most active one in this indolicidin variants.