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Peptide record

TPDB49049

Antifungal standard
41 amino acids
Basic Information
3D PDB MODEL
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TPDB49049
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 41-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
VKSGHYKGPCYHDENCNGVCRDEGYKSGHCSRWGGACWCDT
Physicochemical Analysis
C190H274N60O61S6
QILMF
G
4566.99
7.00
8
5
8
+0
9.10
-1.044
16.59
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
15845
346.95
15
Residue Composition
number
1
A
2
R
2
N
3
D
6
C
2
E
0
Q
7
G
3
H
0
I
0
L
3
K
0
M
0
F
1
P
3
S
1
T
2
W
3
Y
2
V
Amino Acid Distribution
A: 1 R: 2 N: 2 D: 3 C: 6 E: 2 Q: 0 G: 7 H: 3 I: 0 L: 0 K: 3 M: 0 F: 0 P: 1 S: 3 T: 1 W: 2 Y: 3 V: 2
Chemical Descriptors
41
C190H274N60O61S6
4566.99
7.00
+0
9.10
-1.044
Evidence Records 1 records
Evidence 1 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
zone diffusion assay: Active against A. niger (CL 14.9 uM), A. nidulans RCho15 or RCho10 or tCho4 (CL 0.7-1.5 uM), G. candidum (CL 4.7 uM), N. crassa (CL 0.6 uM), C. albicans 16 strains (CL 1.8-26 uM), (CL 14.9 uM), C. tropicalis JX1009 or JX1016 or JX1017 (CL 8.8 uM), S. cerevisiae (CL 6.7 uM). Updated 7/2021, 11/2023