TPDB

3D PDB MODEL

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TPDB ID TPDB49047

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 55-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

KTCSDGWTCLGPKEEDKCKENCMAKHKGVGTCNLYTIPEFPAPITYYMCDCMFDC

FASTA

>TPDB49047|Antifungal|length=55
KTCSDGWTCLGPKEEDKCKENCMAKHKGVGTCNLYTIPEFPAPITYYMCDCMFDC

Formula C267H406N66O83S11

Absent Amino Acids RQ

Common Amino Acids C

Mass 6221.21

PI 4.90

Basic Residues 7

Acidic Residues 8

Hydrophobic Residues 16

Net Charge -2

Boman Index 11.86

Hydrophobicity -0.418

Aliphatic Index 37.27

Half Life

Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min

Extinction Coefficient Cystines 10470

Absorbance 280nm 168.30

Polar Residues 19

number

2

A

0

R

2

N

4

D

8

C

4

E

0

Q

4

G

1

H

2

I

2

L

6

K

3

M

2

F

4

P

1

S

5

T

1

W

3

Y

1

V

Amino Acid Distribution

A: 2 R: 0 N: 2 D: 4 C: 8 E: 4 Q: 0 G: 4 H: 1 I: 2 L: 2 K: 6 M: 3 F: 2 P: 4 S: 1 T: 5 W: 1 Y: 3 V: 1

Length

55

Formula

C267H406N66O83S11

Mass

6221.21

PI

4.90

Net Charge

-2

Boman Index

11.86

Hydrophobicity

-0.418

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.