TPDB

3D PDB MODEL

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TPDB ID TPDB49045

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 52-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

QEMCRDILMKAKNCDEGTCDTLCKQKWKGNGSCFPNVYTYRKSCLCTFPCKT

FASTA

>TPDB49045|Antifungal|length=52
QEMCRDILMKAKNCDEGTCDTLCKQKWKGNGSCFPNVYTYRKSCLCTFPCKT

Formula C253H403N71O77S10

Absent Amino Acids H

Common Amino Acids C

Mass 5992.01

PI 8.30

Basic Residues 9

Acidic Residues 5

Hydrophobic Residues 13

Net Charge +4

Boman Index 10.13

Hydrophobicity -0.635

Aliphatic Index 37.50

Half Life

Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour

Extinction Coefficient Cystines 8980

Absorbance 280nm 149.87

Polar Residues 22

number

1

A

2

R

3

N

3

D

8

C

2

E

2

Q

3

G

0

H

1

I

3

L

7

K

2

M

2

F

2

P

2

S

5

T

1

W

2

Y

1

V

Amino Acid Distribution

A: 1 R: 2 N: 3 D: 3 C: 8 E: 2 Q: 2 G: 3 H: 0 I: 1 L: 3 K: 7 M: 2 F: 2 P: 2 S: 2 T: 5 W: 1 Y: 2 V: 1

Length

52

Formula

C253H403N71O77S10

Mass

5992.01

PI

8.30

Net Charge

+4

Boman Index

10.13

Hydrophobicity

-0.635

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.