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Peptide record

TPDB49045

Antifungal standard
52 amino acids
Basic Information
3D PDB MODEL
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TPDB49045
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 52-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
QEMCRDILMKAKNCDEGTCDTLCKQKWKGNGSCFPNVYTYRKSCLCTFPCKT
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C253H403N71O77S10
H
C
5992.01
8.30
9
5
13
+4
2.07
-0.635
37.50
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
8980
1.50
22
Residue Composition
number
1
A
2
R
3
N
3
D
8
C
2
E
2
Q
3
G
0
H
1
I
3
L
7
K
2
M
2
F
2
P
2
S
5
T
1
W
2
Y
1
V
Amino Acid Distribution
A: 1 R: 2 N: 3 D: 3 C: 8 E: 2 Q: 2 G: 3 H: 0 I: 1 L: 3 K: 7 M: 2 F: 2 P: 2 S: 2 T: 5 W: 1 Y: 2 V: 1
Chemical Descriptors
52 reviewed residue count
C253H403N71O77S10 sequence-only estimate (linear, free termini)
5992.01 sequence-only estimate (linear, free termini)
8.30 sequence-only estimate (linear, free termini)
+4 sequence-only estimate (linear, free termini)
2.07 sequence-only estimate (linear, free termini)
-0.635 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.