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Peptide record

TPDB49044

Antifungal standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB49044
Antifungal
Anti-infective peptides
AFP-GFuse
standard
No
A 14-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, with an available 3D structural model.
Sequence
MMMMRMQQEEMQPR
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C72H125N23O22S6
ANDCGHILKFSTWYV
M
1857.29
7.12
2
2
6
+0
3.28
-1.193
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
2
E
3
Q
0
G
0
H
0
I
0
L
0
K
6
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 2 Q: 3 G: 0 H: 0 I: 0 L: 0 K: 0 M: 6 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
14 reviewed residue count
C72H125N23O22S6 sequence-only estimate (linear, free termini)
1857.29 sequence-only estimate (linear, free termini)
7.12 sequence-only estimate (linear, free termini)
+0 sequence-only estimate (linear, free termini)
3.28 sequence-only estimate (linear, free termini)
-1.193 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

Antifungal

Source & Reference

NA

Other

active against fungi C. albicans and C. tropicalis (50-200 ug/ml). It also inhibited trypsin enzyme activity.