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Peptide record

TPDB49039

Antifungal standard
93 amino acids
Basic Information
3D PDB MODEL
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TPDB49039
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 93-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
QTCDENLSSCENCDQRCKAKHGPSSVSKCNGPDGTCGCASFKPAKLCIGATDMCTDKCPTSCCDRQCAIKYKNGKGGCVDYAGYRMCICEYTC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C399H640N120O138S19
W
C
9935.33
7.46
13
10
20
+1
1.96
-0.504
33.66
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
6960
0.70
41
Residue Composition
number
6
A
3
R
4
N
7
D
17
C
3
E
3
Q
9
G
1
H
3
I
2
L
9
K
2
M
1
F
4
P
7
S
6
T
0
W
4
Y
2
V
Amino Acid Distribution
A: 6 R: 3 N: 4 D: 7 C: 17 E: 3 Q: 3 G: 9 H: 1 I: 3 L: 2 K: 9 M: 2 F: 1 P: 4 S: 7 T: 6 W: 0 Y: 4 V: 2
Chemical Descriptors
93 reviewed residue count
C399H640N120O138S19 sequence-only estimate (linear, free termini)
9935.33 sequence-only estimate (linear, free termini)
7.46 sequence-only estimate (linear, free termini)
+1 sequence-only estimate (linear, free termini)
1.96 sequence-only estimate (linear, free termini)
-0.504 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.