TPDB

3D PDB MODEL

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TPDB ID TPDB49034

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 58-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

TEMMAVEGRICERRSKTWTGFCGNTRGCDSQCKRWERASHGACHAQFPGFACFCYFNC

FASTA

>TPDB49034|Antifungal|length=58
TEMMAVEGRICERRSKTWTGFCGNTRGCDSQCKRWERASHGACHAQFPGFACFCYFNC

Formula C280H418N88O81S10

Absent Amino Acids L

Common Amino Acids C

Mass 6633.54

PI 8.10

Basic Residues 10

Acidic Residues 5

Hydrophobic Residues 17

Net Charge +3

Boman Index 7.77

Hydrophobicity -0.509

Aliphatic Index 20.34

Half Life

Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 12990

Absorbance 280nm 195.82

Polar Residues 20

number

5

A

6

R

2

N

1

D

8

C

4

E

2

Q

6

G

2

H

1

I

0

L

2

K

2

M

5

F

1

P

3

S

4

T

2

W

1

Y

1

V

Amino Acid Distribution

A: 5 R: 6 N: 2 D: 1 C: 8 E: 4 Q: 2 G: 6 H: 2 I: 1 L: 0 K: 2 M: 2 F: 5 P: 1 S: 3 T: 4 W: 2 Y: 1 V: 1

Length

58

Formula

C280H418N88O81S10

Mass

6633.54

PI

8.10

Net Charge

+3

Boman Index

7.77

Hydrophobicity

-0.509

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.