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Peptide record

TPDB49028

Antifungal standard
56 amino acids
Basic Information
3D PDB MODEL
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TPDB49028
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 56-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
LSNSDILVSSVIETSKYDVCFIPCTRRYEDRECNDDCLAKDFNDGGCVDGRCCCKY
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C263H412N74O92S8
QHMW
DC
6339.09
4.22
7
11
16
-4
2.54
-0.387
64.29
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
4970
0.78
21
Residue Composition
number
1
A
4
R
3
N
8
D
8
C
3
E
0
Q
3
G
0
H
3
I
3
L
3
K
0
M
2
F
1
P
5
S
2
T
0
W
3
Y
4
V
Amino Acid Distribution
A: 1 R: 4 N: 3 D: 8 C: 8 E: 3 Q: 0 G: 3 H: 0 I: 3 L: 3 K: 3 M: 0 F: 2 P: 1 S: 5 T: 2 W: 0 Y: 3 V: 4
Chemical Descriptors
56 reviewed residue count
C263H412N74O92S8 sequence-only estimate (linear, free termini)
6339.09 sequence-only estimate (linear, free termini)
4.22 sequence-only estimate (linear, free termini)
-4 sequence-only estimate (linear, free termini)
2.54 sequence-only estimate (linear, free termini)
-0.387 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.