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Peptide record

TPDB49027

Antifungal standard
73 amino acids
Basic Information
3D PDB MODEL
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TPDB49027
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 73-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
QGKKKPPCPLGLSANGKCGHDGPKLCFSEMERKFNKDVVKTITHCKCWDDRRNNVDKHRCTCYLKHGFPCTNG
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C354H563N111O101S9
K
8278.59
9.22
19
7
15
+8
2.51
-0.989
40.00
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
7490
0.90
21
Residue Composition
number
1
A
4
R
5
N
5
D
8
C
2
E
1
Q
7
G
4
H
1
I
4
L
11
K
1
M
3
F
5
P
2
S
4
T
1
W
1
Y
3
V
Amino Acid Distribution
A: 1 R: 4 N: 5 D: 5 C: 8 E: 2 Q: 1 G: 7 H: 4 I: 1 L: 4 K: 11 M: 1 F: 3 P: 5 S: 2 T: 4 W: 1 Y: 1 V: 3
Chemical Descriptors
73 reviewed residue count
C354H563N111O101S9 sequence-only estimate (linear, free termini)
8278.59 sequence-only estimate (linear, free termini)
9.22 sequence-only estimate (linear, free termini)
+8 sequence-only estimate (linear, free termini)
2.51 sequence-only estimate (linear, free termini)
-0.989 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.