TPDB

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

TPDB ID TPDB49027

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 73-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

QGKKKPPCPLGLSANGKCGHDGPKLCFSEMERKFNKDVVKTITHCKCWDDRRNNVDKHRCTCYLKHGFPCTNG

FASTA

>TPDB49027|Antifungal|length=73
QGKKKPPCPLGLSANGKCGHDGPKLCFSEMERKFNKDVVKTITHCKCWDDRRNNVDKHRCTCYLKHGFPCTNG

Formula C354H563N111O101S9

Absent Amino Acids

Common Amino Acids K

Mass 8278.59

PI 9.22

Basic Residues 19

Acidic Residues 7

Hydrophobic Residues 15

Net Charge +8

Boman Index 23.14

Hydrophobicity -0.989

Aliphatic Index 40.00

Half Life

Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour

Extinction Coefficient Cystines 7490

Absorbance 280nm 90.47

Polar Residues 21

number

1

A

4

R

5

N

5

D

8

C

2

E

1

Q

7

G

4

H

1

I

4

L

11

K

1

M

3

F

5

P

2

S

4

T

1

W

1

Y

3

V

Amino Acid Distribution

A: 1 R: 4 N: 5 D: 5 C: 8 E: 2 Q: 1 G: 7 H: 4 I: 1 L: 4 K: 11 M: 1 F: 3 P: 5 S: 2 T: 4 W: 1 Y: 1 V: 3

Length

73

Formula

C354H563N111O101S9

Mass

8278.59

PI

9.22

Net Charge

+8

Boman Index

23.14

Hydrophobicity

-0.989

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.