TPDB

3D PDB MODEL

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TPDB ID TPDB49026

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 55-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

AETTKFSYDHCFHLCVEGEYGSRECFVDCTQKGFWHGVCANKTTAKDPIHCCCYN

FASTA

>TPDB49026|Antifungal|length=55
AETTKFSYDHCFHLCVEGEYGSRECFVDCTQKGFWHGVCANKTTAKDPIHCCCYN

Formula C272H394N74O83S8

Absent Amino Acids M

Common Amino Acids C

Mass 6285.05

PI 6.02

Basic Residues 9

Acidic Residues 7

Hydrophobic Residues 16

Net Charge -2

Boman Index 10.97

Hydrophobicity -0.427

Aliphatic Index 35.45

Half Life

Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 10470

Absorbance 280nm 166.59

Polar Residues 21

number

3

A

1

R

2

N

3

D

8

C

4

E

1

Q

4

G

4

H

1

I

1

L

4

K

0

M

4

F

1

P

2

S

5

T

1

W

3

Y

3

V

Amino Acid Distribution

A: 3 R: 1 N: 2 D: 3 C: 8 E: 4 Q: 1 G: 4 H: 4 I: 1 L: 1 K: 4 M: 0 F: 4 P: 1 S: 2 T: 5 W: 1 Y: 3 V: 3

Length

55

Formula

C272H394N74O83S8

Mass

6285.05

PI

6.02

Net Charge

-2

Boman Index

10.97

Hydrophobicity

-0.427

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.