TPDB

3D PDB MODEL

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TPDB ID TPDB49017

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 52-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

DTCHEYLYPEKCENNQCNSECATKFKEVGVFGFCVPPRSEPTEQFCICSYNC

FASTA

>TPDB49017|Antifungal|length=52
DTCHEYLYPEKCENNQCNSECATKFKEVGVFGFCVPPRSEPTEQFCICSYNC

Formula C257H378N66O84S8

Absent Amino Acids MW

Common Amino Acids C

Mass 5992.70

PI 4.42

Basic Residues 5

Acidic Residues 8

Hydrophobic Residues 13

Net Charge -4

Boman Index 15.49

Hydrophobicity -0.579

Aliphatic Index 33.65

Half Life

Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour

Extinction Coefficient Cystines 4970

Absorbance 280nm 82.93

Polar Residues 23

number

1

A

1

R

4

N

1

D

8

C

7

E

2

Q

2

G

1

H

1

I

1

L

3

K

0

M

4

F

4

P

3

S

3

T

0

W

3

Y

3

V

Amino Acid Distribution

A: 1 R: 1 N: 4 D: 1 C: 8 E: 7 Q: 2 G: 2 H: 1 I: 1 L: 1 K: 3 M: 0 F: 4 P: 4 S: 3 T: 3 W: 0 Y: 3 V: 3

Length

52

Formula

C257H378N66O84S8

Mass

5992.70

PI

4.42

Net Charge

-4

Boman Index

15.49

Hydrophobicity

-0.579

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.