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Peptide record

TPDB49017

Antifungal standard
52 amino acids
Basic Information
3D PDB MODEL
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TPDB49017
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 52-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
DTCHEYLYPEKCENNQCNSECATKFKEVGVFGFCVPPRSEPTEQFCICSYNC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C257H378N66O84S8
MW
C
5992.70
4.42
5
8
13
-4
1.94
-0.579
33.65
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
4970
0.83
23
Residue Composition
number
1
A
1
R
4
N
1
D
8
C
7
E
2
Q
2
G
1
H
1
I
1
L
3
K
0
M
4
F
4
P
3
S
3
T
0
W
3
Y
3
V
Amino Acid Distribution
A: 1 R: 1 N: 4 D: 1 C: 8 E: 7 Q: 2 G: 2 H: 1 I: 1 L: 1 K: 3 M: 0 F: 4 P: 4 S: 3 T: 3 W: 0 Y: 3 V: 3
Chemical Descriptors
52 reviewed residue count
C257H378N66O84S8 sequence-only estimate (linear, free termini)
5992.70 sequence-only estimate (linear, free termini)
4.42 sequence-only estimate (linear, free termini)
-4 sequence-only estimate (linear, free termini)
1.94 sequence-only estimate (linear, free termini)
-0.579 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.