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Peptide record

TPDB49011

Antifungal standard
61 amino acids
Basic Information
3D PDB MODEL
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TPDB49011
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 61-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
NMGCTATMGPCEKDKSCSATCRATFGDRANGFCDYSTSTSPGGECTCVYHCPPVVPHESHL
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C263H403N77O91S10
QIW
C
6420.15
5.77
7
6
14
-2
1.68
-0.395
27.21
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
3480
0.54
25
Residue Composition
number
4
A
2
R
2
N
3
D
8
C
3
E
0
Q
6
G
3
H
0
I
1
L
2
K
2
M
2
F
5
P
6
S
7
T
0
W
2
Y
3
V
Amino Acid Distribution
A: 4 R: 2 N: 2 D: 3 C: 8 E: 3 Q: 0 G: 6 H: 3 I: 0 L: 1 K: 2 M: 2 F: 2 P: 5 S: 6 T: 7 W: 0 Y: 2 V: 3
Chemical Descriptors
61 reviewed residue count
C263H403N77O91S10 sequence-only estimate (linear, free termini)
6420.15 sequence-only estimate (linear, free termini)
5.77 sequence-only estimate (linear, free termini)
-2 sequence-only estimate (linear, free termini)
1.68 sequence-only estimate (linear, free termini)
-0.395 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.