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Peptide record

TPDB49010

Antifungal standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB49010
Antifungal
Anti-infective peptides
AFP-GFuse
standard
No
A 33-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, with an available 3D structural model.
Sequence
GQQSCLCGYMKQYVNSPNARKVVGQCGVSVPNC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C146H237N45O46S5
DEHIFTW
V
3519.06
8.70
3
0
10
+3
1.22
-0.245
58.79
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
3230
0.92
16
Residue Composition
number
1
A
1
R
3
N
0
D
4
C
0
E
4
Q
4
G
0
H
0
I
1
L
2
K
1
M
0
F
2
P
3
S
0
T
0
W
2
Y
5
V
Amino Acid Distribution
A: 1 R: 1 N: 3 D: 0 C: 4 E: 0 Q: 4 G: 4 H: 0 I: 0 L: 1 K: 2 M: 1 F: 0 P: 2 S: 3 T: 0 W: 0 Y: 2 V: 5
Chemical Descriptors
33 reviewed residue count
C146H237N45O46S5 sequence-only estimate (linear, free termini)
3519.06 sequence-only estimate (linear, free termini)
8.70 sequence-only estimate (linear, free termini)
+3 sequence-only estimate (linear, free termini)
1.22 sequence-only estimate (linear, free termini)
-0.245 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

Antifungal

Source & Reference

NA

Other

treated at 200 ug/ml (56.8 uM), changed viability of C. albicans and C. buinensis.