TPDB

3D PDB MODEL

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TPDB ID TPDB49009

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 59-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

RRVCDSAAGLCSMLFSCNTQCNSLGRNFTGGECSDARFPGLSVCYCCHNVESSAEMESM

FASTA

>TPDB49009|Antifungal|length=59
RRVCDSAAGLCSMLFSCNTQCNSLGRNFTGGECSDARFPGLSVCYCCHNVESSAEMESM

Formula C255H402N78O89S11

Absent Amino Acids IKW

Common Amino Acids S

Mass 6337.13

PI 4.81

Basic Residues 5

Acidic Residues 6

Hydrophobic Residues 18

Net Charge -2

Boman Index 9.30

Hydrophobicity -0.069

Aliphatic Index 47.97

Half Life

Mammalian: 1 hour Yeast: 2 min E.coli: 2 min

Extinction Coefficient Cystines 1990

Absorbance 280nm 31.40

Polar Residues 25

number

4

A

4

R

4

N

2

D

8

C

4

E

1

Q

5

G

1

H

0

I

4

L

0

K

3

M

3

F

1

P

9

S

2

T

0

W

1

Y

3

V

Amino Acid Distribution

A: 4 R: 4 N: 4 D: 2 C: 8 E: 4 Q: 1 G: 5 H: 1 I: 0 L: 4 K: 0 M: 3 F: 3 P: 1 S: 9 T: 2 W: 0 Y: 1 V: 3

Length

59

Formula

C255H402N78O89S11

Mass

6337.13

PI

4.81

Net Charge

-2

Boman Index

9.30

Hydrophobicity

-0.069

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.