Back to search

Peptide record

TPDB49005

Antifungal standard
50 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB49005
Antifungal
Anti-infective peptides
AFP-GFuse
standard
No
A 50-aa standard natural antifungal peptide sequence curated from AFP-GFuse, with an available 3D structural model.
Sequence
RMCESQSHKFKGYCASSSNCKVVCQTEKFLTGSCRDTHFGNRRCFCEKPC
Physicochemical Analysis
C237H373N75O73S9
IW
C
5729.57
8.52
11
4
10
+5
12.88
-0.716
21.40
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1990
34.73
22
Residue Composition
number
1
A
4
R
2
N
1
D
8
C
3
E
2
Q
3
G
2
H
0
I
1
L
5
K
1
M
4
F
1
P
6
S
3
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 1 R: 4 N: 2 D: 1 C: 8 E: 3 Q: 2 G: 3 H: 2 I: 0 L: 1 K: 5 M: 1 F: 4 P: 1 S: 6 T: 3 W: 0 Y: 1 V: 2
Chemical Descriptors
50
C237H373N75O73S9
5729.57
8.52
+5
12.88
-0.716
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
Antifungal
2 µg/mL

Target

V. dahliae

Source & Reference

NA

Other

inhibited the fungal growth V. dahliae (IC50 2 ug/ml), B. cinerea (IC50 4 ug/ml), and F. oxysporum (IC50 11 ug/ml). Completely inhibited spores
Evidence 2 Activity

Activity

IC50
Antifungal
4 µg/mL

Target

B. cinerea

Source & Reference

NA

Other

inhibited the fungal growth V. dahliae (IC50 2 ug/ml), B. cinerea (IC50 4 ug/ml), and F. oxysporum (IC50 11 ug/ml). Completely inhibited spores of V. dahliae at 8 ug/ml.
Evidence 3 Activity

Activity

IC50
Antifungal
11 µg/mL

Target

F. oxysporum

Source & Reference

NA

Other

inhibited the fungal growth V. dahliae (IC50 2 ug/ml), B. cinerea (IC50 4 ug/ml), and F. oxysporum (IC50 11 ug/ml). Completely inhibited spores of V. dahliae at 8 ug/ml.