TPDB

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

TPDB ID TPDB49003

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 57-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

NCDTYLGEVTVYYPCRERDCEAQCYEHYPHSCKGECEHHDHVVHHDNEEEHCHCYGR

FASTA

>TPDB49003|Antifungal|length=57
NCDTYLGEVTVYYPCRERDCEAQCYEHYPHSCKGECEHHDHVVHHDNEEEHCHCYGR

Formula C286H404N88O96S8

Absent Amino Acids IMFW

Common Amino Acids EH

Mass 6867.37

PI 5.17

Basic Residues 13

Acidic Residues 13

Hydrophobic Residues 12

Net Charge -9

Boman Index 29.91

Hydrophobicity -1.302

Aliphatic Index 28.95

Half Life

Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour

Extinction Coefficient Cystines 9440

Absorbance 280nm 137.46

Polar Residues 20

number

1

A

3

R

2

N

4

D

8

C

9

E

1

Q

3

G

9

H

0

I

1

L

1

K

0

M

0

F

2

P

1

S

2

T

0

W

6

Y

4

V

Amino Acid Distribution

A: 1 R: 3 N: 2 D: 4 C: 8 E: 9 Q: 1 G: 3 H: 9 I: 0 L: 1 K: 1 M: 0 F: 0 P: 2 S: 1 T: 2 W: 0 Y: 6 V: 4

Length

57

Formula

C286H404N88O96S8

Mass

6867.37

PI

5.17

Net Charge

-9

Boman Index

29.91

Hydrophobicity

-1.302

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.