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Peptide record

TPDB49002

Antifungal standard
77 amino acids
Basic Information
3D PDB MODEL
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TPDB49002
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 77-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
QSCNNDSDCTNLKCATKNIKCEQNKCQCLDERYIRAISLNTRSPRCNVQSCIDHCKAIGEVIYVCFTYHCYCRKPPM
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C369H595N113O116S13
W
C
8887.25
8.02
13
7
21
+4
2.41
-0.538
60.78
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
6710
0.76
36
Residue Composition
number
3
A
5
R
7
N
4
D
12
C
3
E
4
Q
1
G
2
H
6
I
3
L
6
K
1
M
1
F
3
P
5
S
4
T
0
W
4
Y
3
V
Amino Acid Distribution
A: 3 R: 5 N: 7 D: 4 C: 12 E: 3 Q: 4 G: 1 H: 2 I: 6 L: 3 K: 6 M: 1 F: 1 P: 3 S: 5 T: 4 W: 0 Y: 4 V: 3
Chemical Descriptors
77 reviewed residue count
C369H595N113O116S13 sequence-only estimate (linear, free termini)
8887.25 sequence-only estimate (linear, free termini)
8.02 sequence-only estimate (linear, free termini)
+4 sequence-only estimate (linear, free termini)
2.41 sequence-only estimate (linear, free termini)
-0.538 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.