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Peptide record

TPDB49000

Antifungal standard
58 amino acids
Basic Information
3D PDB MODEL
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TPDB49000
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 58-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
YCERVRSRSAPHDICKKKNGNAVCKEKCWTIEKYQNGRCLILPKTTKLDCYCYHFDQC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C297H470N88O85S8
M
CK
6890.02
8.70
14
6
16
+6
2.54
-0.831
53.79
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
11960
1.74
22
Residue Composition
number
2
A
4
R
3
N
3
D
8
C
3
E
2
Q
2
G
2
H
3
I
3
L
8
K
0
M
1
F
2
P
2
S
3
T
1
W
4
Y
2
V
Amino Acid Distribution
A: 2 R: 4 N: 3 D: 3 C: 8 E: 3 Q: 2 G: 2 H: 2 I: 3 L: 3 K: 8 M: 0 F: 1 P: 2 S: 2 T: 3 W: 1 Y: 4 V: 2
Chemical Descriptors
58 reviewed residue count
C297H470N88O85S8 sequence-only estimate (linear, free termini)
6890.02 sequence-only estimate (linear, free termini)
8.70 sequence-only estimate (linear, free termini)
+6 sequence-only estimate (linear, free termini)
2.54 sequence-only estimate (linear, free termini)
-0.831 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.