TPDB

3D PDB MODEL

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TPDB ID TPDB48996

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 60-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

MIYNVESGGSLCCNSHPKFGKCNTNNDEQRCNRWCHNGCGNGKGGYYKSMSHGGQCHYYC

FASTA

>TPDB48996|Antifungal|length=60
MIYNVESGGSLCCNSHPKFGKCNTNNDEQRCNRWCHNGCGNGKGGYYKSMSHGGQCHYYC

Formula C276H407N89O88S10

Absent Amino Acids A

Common Amino Acids G

Mass 6700.41

PI 8.09

Basic Residues 10

Acidic Residues 3

Hydrophobic Residues 12

Net Charge +3

Boman Index 9.69

Hydrophobicity -1.025

Aliphatic Index 17.83

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 13450

Absorbance 280nm 200.73

Polar Residues 29

number

0

A

2

R

8

N

1

D

8

C

2

E

2

Q

10

G

4

H

1

I

1

L

4

K

2

M

1

F

1

P

5

S

1

T

1

W

5

Y

1

V

Amino Acid Distribution

A: 0 R: 2 N: 8 D: 1 C: 8 E: 2 Q: 2 G: 10 H: 4 I: 1 L: 1 K: 4 M: 2 F: 1 P: 1 S: 5 T: 1 W: 1 Y: 5 V: 1

Length

60

Formula

C276H407N89O88S10

Mass

6700.41

PI

8.09

Net Charge

+3

Boman Index

9.69

Hydrophobicity

-1.025

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.