TPDB

3D PDB MODEL

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TPDB ID TPDB48992

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 44-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

PVSRQQCSQRIQGERFNQCRSQMQDGQLQSCCQELQNVEEQCQC

FASTA

>TPDB48992|Antifungal|length=44
PVSRQQCSQRIQGERFNQCRSQMQDGQLQSCCQELQNVEEQCQC

Formula C202H331N71O74S7

Absent Amino Acids AHKTWY

Common Amino Acids Q

Mass 5162.70

PI 4.79

Basic Residues 4

Acidic Residues 5

Hydrophobic Residues 7

Net Charge -1

Boman Index 17.83

Hydrophobicity -1.214

Aliphatic Index 39.77

Half Life

Mammalian: >20 hour Yeast: >20 hour E.coli: ?

Extinction Coefficient Cystines 375

Absorbance 280nm 7.26

Polar Residues 25

number

0

A

4

R

2

N

1

D

6

C

4

E

13

Q

2

G

0

H

1

I

2

L

0

K

1

M

1

F

1

P

4

S

0

T

0

W

0

Y

2

V

Amino Acid Distribution

A: 0 R: 4 N: 2 D: 1 C: 6 E: 4 Q: 13 G: 2 H: 0 I: 1 L: 2 K: 0 M: 1 F: 1 P: 1 S: 4 T: 0 W: 0 Y: 0 V: 2

Length

44

Formula

C202H331N71O74S7

Mass

5162.70

PI

4.79

Net Charge

-1

Boman Index

17.83

Hydrophobicity

-1.214

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.