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Peptide record

TPDB48991

Antifungal standard
86 amino acids
Basic Information
3D PDB MODEL
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TPDB48991
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 86-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
LIYAKVECLTTGVRTYVGKQSWPELVGTKGKTAAATIDKENTHVTAVLCPPLTTLAACRTFDFRCDRVRVLINRIGGVVTKTPTVG
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C412H682N116O119S4
M
T
9292.89
9.76
13
6
34
+6
1.18
0.123
95.12
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
8730
0.94
24
Residue Composition
number
7
A
6
R
2
N
3
D
4
C
3
E
1
Q
7
G
1
H
4
I
7
L
6
K
0
M
2
F
4
P
1
S
14
T
1
W
2
Y
11
V
Amino Acid Distribution
A: 7 R: 6 N: 2 D: 3 C: 4 E: 3 Q: 1 G: 7 H: 1 I: 4 L: 7 K: 6 M: 0 F: 2 P: 4 S: 1 T: 14 W: 1 Y: 2 V: 11
Chemical Descriptors
86 reviewed residue count
C412H682N116O119S4 sequence-only estimate (linear, free termini)
9292.89 sequence-only estimate (linear, free termini)
9.76 sequence-only estimate (linear, free termini)
+6 sequence-only estimate (linear, free termini)
1.18 sequence-only estimate (linear, free termini)
0.123 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.