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Peptide record

TPDB48990

Antifungal standard
56 amino acids
Basic Information
3D PDB MODEL
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TPDB48990
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 56-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
SDARIEGFSFDNCNIRCSEDYWNDECNKDCLRAGFQKGGQCGSPCIPCPVKCCCQK
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C257H395N77O85S10
HMT
C
6244.03
4.88
7
8
12
-1
2.35
-0.630
36.61
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
7615
1.22
22
Residue Composition
number
2
A
3
R
4
N
5
D
10
C
3
E
3
Q
5
G
0
H
3
I
1
L
4
K
0
M
3
F
3
P
4
S
0
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 2 R: 3 N: 4 D: 5 C: 10 E: 3 Q: 3 G: 5 H: 0 I: 3 L: 1 K: 4 M: 0 F: 3 P: 3 S: 4 T: 0 W: 1 Y: 1 V: 1
Chemical Descriptors
56 reviewed residue count
C257H395N77O85S10 sequence-only estimate (linear, free termini)
6244.03 sequence-only estimate (linear, free termini)
4.88 sequence-only estimate (linear, free termini)
-1 sequence-only estimate (linear, free termini)
2.35 sequence-only estimate (linear, free termini)
-0.630 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.