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Peptide record

TPDB48975

Antifungal standard
46 amino acids
Basic Information
3D PDB MODEL
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TPDB48975
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 46-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
RVCESQSHGFHGLCNRDHNCALVCRNEGFSGGRCKRSRRCFCTRIC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C211H341N81O62S8
MPWY
RC
5261.01
8.77
12
3
9
+6
3.35
-0.635
40.22
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
500
0.10
17
Residue Composition
number
1
A
8
R
3
N
1
D
8
C
2
E
1
Q
5
G
3
H
1
I
2
L
1
K
0
M
3
F
0
P
4
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 8 N: 3 D: 1 C: 8 E: 2 Q: 1 G: 5 H: 3 I: 1 L: 2 K: 1 M: 0 F: 3 P: 0 S: 4 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
46 reviewed residue count
C211H341N81O62S8 sequence-only estimate (linear, free termini)
5261.01 sequence-only estimate (linear, free termini)
8.77 sequence-only estimate (linear, free termini)
+6 sequence-only estimate (linear, free termini)
3.35 sequence-only estimate (linear, free termini)
-0.635 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.