TPDB

3D PDB MODEL

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TPDB ID TPDB48972

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 46-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

QLKSTCRIAEAWKGAKECNAKCAALGTTRGGVCQKFLGDLYCCCWD

FASTA

>TPDB48972|Antifungal|length=46
QLKSTCRIAEAWKGAKECNAKCAALGTTRGGVCQKFLGDLYCCCWD

Formula C213H340N62O63S7

Absent Amino Acids HMP

Common Amino Acids C

Mass 5001.84

PI 8.19

Basic Residues 7

Acidic Residues 4

Hydrophobic Residues 16

Net Charge +3

Boman Index 4.30

Hydrophobicity -0.130

Aliphatic Index 61.74

Half Life

Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour

Extinction Coefficient Cystines 12865

Absorbance 280nm 257.21

Polar Residues 15

number

6

A

2

R

1

N

2

D

7

C

2

E

2

Q

5

G

0

H

1

I

4

L

5

K

0

M

1

F

0

P

1

S

3

T

2

W

1

Y

1

V

Amino Acid Distribution

A: 6 R: 2 N: 1 D: 2 C: 7 E: 2 Q: 2 G: 5 H: 0 I: 1 L: 4 K: 5 M: 0 F: 1 P: 0 S: 1 T: 3 W: 2 Y: 1 V: 1

Length

46

Formula

C213H340N62O63S7

Mass

5001.84

PI

8.19

Net Charge

+3

Boman Index

4.30

Hydrophobicity

-0.130

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.