TPDB

3D PDB MODEL

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TPDB ID TPDB48967

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 59-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

VEMGISVQALPPTCGPDCTGRFMNQDCSKYCAALSYKHGVCILFRGLPPRTSTLRCCCG

FASTA

>TPDB48967|Antifungal|length=59
VEMGISVQALPPTCGPDCTGRFMNQDCSKYCAALSYKHGVCILFRGLPPRTSTLRCCCG

Formula C270H434N78O79S10

Absent Amino Acids W

Common Amino Acids C

Mass 6357.49

PI 8.10

Basic Residues 7

Acidic Residues 3

Hydrophobic Residues 19

Net Charge +3

Boman Index 5.39

Hydrophobicity 0.108

Aliphatic Index 66.10

Half Life

Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 3480

Absorbance 280nm 54.74

Polar Residues 21

number

3

A

4

R

1

N

2

D

8

C

1

E

2

Q

6

G

1

H

2

I

5

L

2

K

2

M

2

F

5

P

4

S

4

T

0

W

2

Y

3

V

Amino Acid Distribution

A: 3 R: 4 N: 1 D: 2 C: 8 E: 1 Q: 2 G: 6 H: 1 I: 2 L: 5 K: 2 M: 2 F: 2 P: 5 S: 4 T: 4 W: 0 Y: 2 V: 3

Length

59

Formula

C270H434N78O79S10

Mass

6357.49

PI

8.10

Net Charge

+3

Boman Index

5.39

Hydrophobicity

0.108

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.