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Peptide record

TPDB48966

Antifungal standard
77 amino acids
Basic Information
3D PDB MODEL
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TPDB48966
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 77-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
YDLFTGIGIDARTVPPTCYESCNATFQNPECNKMCVGLAYKDGSCIYPPPEVDGLPPKRPYFPRCCCNPIILSPPSP
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C375H570N94O110S9
HW
P
8443.75
4.84
6
7
24
-1
1.11
-0.235
60.78
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
7950
0.94
26
Residue Composition
number
3
A
3
R
4
N
4
D
8
C
3
E
1
Q
5
G
0
H
5
I
4
L
3
K
1
M
3
F
14
P
4
S
4
T
0
W
5
Y
3
V
Amino Acid Distribution
A: 3 R: 3 N: 4 D: 4 C: 8 E: 3 Q: 1 G: 5 H: 0 I: 5 L: 4 K: 3 M: 1 F: 3 P: 14 S: 4 T: 4 W: 0 Y: 5 V: 3
Chemical Descriptors
77 reviewed residue count
C375H570N94O110S9 sequence-only estimate (linear, free termini)
8443.75 sequence-only estimate (linear, free termini)
4.84 sequence-only estimate (linear, free termini)
-1 sequence-only estimate (linear, free termini)
1.11 sequence-only estimate (linear, free termini)
-0.235 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.