TPDB

3D PDB MODEL

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TPDB ID TPDB48966

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 77-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

YDLFTGIGIDARTVPPTCYESCNATFQNPECNKMCVGLAYKDGSCIYPPPEVDGLPPKRPYFPRCCCNPIILSPPSP

FASTA

>TPDB48966|Antifungal|length=77
YDLFTGIGIDARTVPPTCYESCNATFQNPECNKMCVGLAYKDGSCIYPPPEVDGLPPKRPYFPRCCCNPIILSPPSP

Formula C375H570N94O110S9

Absent Amino Acids HW

Common Amino Acids P

Mass 8443.75

PI 4.84

Basic Residues 6

Acidic Residues 7

Hydrophobic Residues 24

Net Charge -1

Boman Index 11.74

Hydrophobicity -0.235

Aliphatic Index 60.78

Half Life

Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min

Extinction Coefficient Cystines 7950

Absorbance 280nm 94.15

Polar Residues 26

number

3

A

3

R

4

N

4

D

8

C

3

E

1

Q

5

G

0

H

5

I

4

L

3

K

1

M

3

F

14

P

4

S

4

T

0

W

5

Y

3

V

Amino Acid Distribution

A: 3 R: 3 N: 4 D: 4 C: 8 E: 3 Q: 1 G: 5 H: 0 I: 5 L: 4 K: 3 M: 1 F: 3 P: 14 S: 4 T: 4 W: 0 Y: 5 V: 3

Length

77

Formula

C375H570N94O110S9

Mass

8443.75

PI

4.84

Net Charge

-1

Boman Index

11.74

Hydrophobicity

-0.235

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.