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Peptide record

TPDB48965

Antifungal standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB48965
Antifungal
Anti-infective peptides
AFP-GFuse
standard
No
A 12-aa standard natural antifungal peptide sequence curated from AFP-GFuse, with an available 3D structural model.
Sequence
RLARIWWIRWAR
Physicochemical Analysis
C81H123N27O13
NDCEQGHKMFPSTYV
R
1683.04
12.88
4
0
8
+4
-3.83
-0.358
114.17
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
16500
980.37
0
Residue Composition
number
2
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
12
C81H123N27O13
1683.04
12.88
+4
-3.83
-0.358
Evidence Records 7 records
Evidence 1 Activity

Activity

MIC
Antifungal
50 µg/mL

Target

Pseudomonas aeruginosa PAO1

Source & Reference

NA

Other

active against P. aeruginosa PAO1 (MIC 50 ug/ml), E. coli (MIC 17 ug/ml), S. typhimurium (MIC 34 ug/ml), S. aureus (MIC 17 ug/ml), S. epid
Evidence 2 Activity

Activity

MIC
Antifungal
17 µg/mL

Target

Escherichia coli

Source & Reference

NA

Other

active against P. aeruginosa PAO1 (MIC 50 ug/ml), E. coli (MIC 17 ug/ml), S. typhimurium (MIC 34 ug/ml), S. aureus (MIC 17 ug/ml), S. epidermidis (MIC 4 ug/ml), E
Evidence 3 Activity

Activity

MIC
Antifungal
34 µg/mL

Target

S. typhimurium

Source & Reference

NA

Other

active against P. aeruginosa PAO1 (MIC 50 ug/ml), E. coli (MIC 17 ug/ml), S. typhimurium (MIC 34 ug/ml), S. aureus (MIC 17 ug/ml), S. epidermidis (MIC 4 ug/ml), E. faecalis ATCC29212 (MIC 17 ug
Evidence 4 Activity

Activity

MIC
Antifungal
17 µg/mL

Target

Staphylococcus aureus

Source & Reference

NA

Other

P. aeruginosa PAO1 (MIC 50 ug/ml), E. coli (MIC 17 ug/ml), S. typhimurium (MIC 34 ug/ml), S. aureus (MIC 17 ug/ml), S. epidermidis (MIC 4 ug/ml), E. faecalis ATCC29212 (MIC 17 ug/ml), and C. albicans (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
4 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

NA

Other

ug/ml), E. coli (MIC 17 ug/ml), S. typhimurium (MIC 34 ug/ml), S. aureus (MIC 17 ug/ml), S. epidermidis (MIC 4 ug/ml), E. faecalis ATCC29212 (MIC 17 ug/ml), and C. albicans (MIC 9 ug/ml).
Evidence 6 Activity

Activity

MIC
Antifungal
17 µg/mL

Target

Enterococcus faecalis ATCC29212

Source & Reference

NA

Other

), S. typhimurium (MIC 34 ug/ml), S. aureus (MIC 17 ug/ml), S. epidermidis (MIC 4 ug/ml), E. faecalis ATCC29212 (MIC 17 ug/ml), and C. albicans (MIC 9 ug/ml).
Evidence 7 Activity

Activity

MIC
Antifungal
9 µg/mL

Target

Candida albicans

Source & Reference

NA

Other

s (MIC 17 ug/ml), S. epidermidis (MIC 4 ug/ml), E. faecalis ATCC29212 (MIC 17 ug/ml), and C. albicans (MIC 9 ug/ml).