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Peptide record

TPDB48964

Antifungal standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB48964
Antifungal
Anti-infective peptides
AFP-GFuse
standard
No
A 21-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, with an available 3D structural model.
Sequence
QNLCNIYYIQHADHCLAVINS
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C106H162N30O32S2
REGKMFPTW
NI
2432.75
6.00
2
1
10
-1
0.85
0.148
116.19
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
3105
1.28
10
Residue Composition
number
2
A
0
R
3
N
1
D
2
C
0
E
2
Q
0
G
2
H
3
I
2
L
0
K
0
M
0
F
0
P
1
S
0
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 3 D: 1 C: 2 E: 0 Q: 2 G: 0 H: 2 I: 3 L: 2 K: 0 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 2 V: 1
Chemical Descriptors
21 reviewed residue count
C106H162N30O32S2 sequence-only estimate (linear, free termini)
2432.75 sequence-only estimate (linear, free termini)
6.00 sequence-only estimate (linear, free termini)
-1 sequence-only estimate (linear, free termini)
0.85 sequence-only estimate (linear, free termini)
0.148 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

Antifungal

Source & Reference

NA

Other

active against Gram+ B.subtilis IA274 (- insignificant), C. michiganensis (+++), B.cereus 905 (-), C. fangii (+++), B. subtilis 330-2 (+), B.subtilis RIK1285 (-), B. subtilis 168 (+++), Gram- X. oryzae pv. Oryzae (-), X. oryzae pv. Oryzicola (+++), R. solanacearum (+), X. campestris pv. Holcicola (-). Bacteriostatic.