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Peptide record

TPDB48963

Antifungal standard
58 amino acids
Basic Information
3D PDB MODEL
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TPDB48963
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 58-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
SCDFPLGACTPFRDCKESCIKFKTRAGQTFFDGKCRPRDRPSVWTACFCCYYDSIGAQ
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C287H430N80O83S8
NHM
C
6585.54
8.09
9
6
17
+3
2.11
-0.390
32.07
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
8980
1.36
20
Residue Composition
number
4
A
5
R
0
N
5
D
8
C
1
E
2
Q
4
G
0
H
2
I
1
L
4
K
0
M
6
F
4
P
4
S
4
T
1
W
2
Y
1
V
Amino Acid Distribution
A: 4 R: 5 N: 0 D: 5 C: 8 E: 1 Q: 2 G: 4 H: 0 I: 2 L: 1 K: 4 M: 0 F: 6 P: 4 S: 4 T: 4 W: 1 Y: 2 V: 1
Chemical Descriptors
58 reviewed residue count
C287H430N80O83S8 sequence-only estimate (linear, free termini)
6585.54 sequence-only estimate (linear, free termini)
8.09 sequence-only estimate (linear, free termini)
+3 sequence-only estimate (linear, free termini)
2.11 sequence-only estimate (linear, free termini)
-0.390 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.