TPDB

3D PDB MODEL

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TPDB ID TPDB48956

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 59-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

RSNGIYDPMCPGVCGNLVKPDCNGLCHELGFPAGGYCKPGNTCCCKKKDSGPVDVPPTA

FASTA

>TPDB48956|Antifungal|length=59
RSNGIYDPMCPGVCGNLVKPDCNGLCHELGFPAGGYCKPGNTCCCKKKDSGPVDVPPTA

Formula C257H405N73O80S9

Absent Amino Acids QW

Common Amino Acids G

Mass 6086.02

PI 7.49

Basic Residues 7

Acidic Residues 5

Hydrophobic Residues 14

Net Charge +1

Boman Index 12.36

Hydrophobicity -0.334

Aliphatic Index 49.49

Half Life

Mammalian: 1 hour Yeast: 2 min E.coli: 2 min

Extinction Coefficient Cystines 3480

Absorbance 280nm 57.18

Polar Residues 18

number

2

A

1

R

4

N

4

D

8

C

1

E

0

Q

9

G

1

H

1

I

3

L

5

K

1

M

1

F

8

P

2

S

2

T

0

W

2

Y

4

V

Amino Acid Distribution

A: 2 R: 1 N: 4 D: 4 C: 8 E: 1 Q: 0 G: 9 H: 1 I: 1 L: 3 K: 5 M: 1 F: 1 P: 8 S: 2 T: 2 W: 0 Y: 2 V: 4

Length

59

Formula

C257H405N73O80S9

Mass

6086.02

PI

7.49

Net Charge

+1

Boman Index

12.36

Hydrophobicity

-0.334

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.