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Peptide record

TPDB48954

Antifungal standard
57 amino acids
Basic Information
3D PDB MODEL
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TPDB48954
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 57-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
SDSTLGIGINQDWKKCFSPDPCKKAGTQGCMEFCRTISFLLFGECTSKPDQCCCVTK
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C267H421N71O84S9
HY
C
6258.25
7.48
7
6
14
+1
1.45
-0.247
47.89
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
6000
0.96
22
Residue Composition
number
1
A
1
R
1
N
4
D
8
C
2
E
3
Q
5
G
0
H
3
I
3
L
6
K
1
M
4
F
3
P
5
S
5
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 4 C: 8 E: 2 Q: 3 G: 5 H: 0 I: 3 L: 3 K: 6 M: 1 F: 4 P: 3 S: 5 T: 5 W: 1 Y: 0 V: 1
Chemical Descriptors
57 reviewed residue count
C267H421N71O84S9 sequence-only estimate (linear, free termini)
6258.25 sequence-only estimate (linear, free termini)
7.48 sequence-only estimate (linear, free termini)
+1 sequence-only estimate (linear, free termini)
1.45 sequence-only estimate (linear, free termini)
-0.247 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.