TPDB

3D PDB MODEL

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TPDB ID TPDB48953

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 41-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

EPQCIGSCEMLADCNTACIRMGYLFGQCVGWKTPDMCCCNH

FASTA

>TPDB48953|Antifungal|length=41
EPQCIGSCEMLADCNTACIRMGYLFGQCVGWKTPDMCCCNH

Formula C186H288N52O58S11

Absent Amino Acids

Common Amino Acids C

Mass 4533.31

PI 4.54

Basic Residues 3

Acidic Residues 4

Hydrophobic Residues 13

Net Charge -2

Boman Index 4.07

Hydrophobicity 0.100

Aliphatic Index 50.00

Half Life

Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour

Extinction Coefficient Cystines 7490

Absorbance 280nm 165.22

Polar Residues 16

number

2

A

1

R

2

N

2

D

8

C

2

E

2

Q

4

G

1

H

2

I

2

L

1

K

3

M

1

F

2

P

1

S

2

T

1

W

1

Y

1

V

Amino Acid Distribution

A: 2 R: 1 N: 2 D: 2 C: 8 E: 2 Q: 2 G: 4 H: 1 I: 2 L: 2 K: 1 M: 3 F: 1 P: 2 S: 1 T: 2 W: 1 Y: 1 V: 1

Length

41

Formula

C186H288N52O58S11

Mass

4533.31

PI

4.54

Net Charge

-2

Boman Index

4.07

Hydrophobicity

0.100

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.