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Peptide record

TPDB48950

Antifungal standard
65 amino acids
Basic Information
3D PDB MODEL
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TPDB48950
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 65-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
SEQRTRVSEVVREAEIHDGGQCTDDDICNKNCLDCIARQCIFQQCVCSKRFFPPNSQPNLRVKKH
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C312H505N101O100S7
MWY
C
7495.48
7.57
12
9
16
+1
3.04
-0.763
61.38
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
375
0.05
23
Residue Composition
number
2
A
6
R
4
N
5
D
7
C
4
E
6
Q
2
G
2
H
4
I
2
L
4
K
0
M
3
F
3
P
4
S
2
T
0
W
0
Y
5
V
Amino Acid Distribution
A: 2 R: 6 N: 4 D: 5 C: 7 E: 4 Q: 6 G: 2 H: 2 I: 4 L: 2 K: 4 M: 0 F: 3 P: 3 S: 4 T: 2 W: 0 Y: 0 V: 5
Chemical Descriptors
65 reviewed residue count
C312H505N101O100S7 sequence-only estimate (linear, free termini)
7495.48 sequence-only estimate (linear, free termini)
7.57 sequence-only estimate (linear, free termini)
+1 sequence-only estimate (linear, free termini)
3.04 sequence-only estimate (linear, free termini)
-0.763 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.