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Peptide record

TPDB48949

Antifungal standard
54 amino acids
Basic Information
3D PDB MODEL
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TPDB48949
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 54-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
KKPPCLEGRTAYVSPGPCSNSLCTQDCRPAGYHTGKCKVEWSTPICKCYGCRKV
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C252H402N74O74S8
MF
C
5908.90
8.72
10
3
12
+6
1.74
-0.587
41.48
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
10470
1.77
21
Residue Composition
number
2
A
3
R
1
N
1
D
8
C
2
E
1
Q
5
G
1
H
1
I
2
L
6
K
0
M
0
F
6
P
4
S
4
T
1
W
3
Y
3
V
Amino Acid Distribution
A: 2 R: 3 N: 1 D: 1 C: 8 E: 2 Q: 1 G: 5 H: 1 I: 1 L: 2 K: 6 M: 0 F: 0 P: 6 S: 4 T: 4 W: 1 Y: 3 V: 3
Chemical Descriptors
54 reviewed residue count
C252H402N74O74S8 sequence-only estimate (linear, free termini)
5908.90 sequence-only estimate (linear, free termini)
8.72 sequence-only estimate (linear, free termini)
+6 sequence-only estimate (linear, free termini)
1.74 sequence-only estimate (linear, free termini)
-0.587 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.