TPDB

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

TPDB ID TPDB48943

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 63-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

EKLCTTIGDLDGKCSQDGEKLCMRYMTDQSKKKFLSCTCNNVVMLHKYKHYCECQSHCTPKQT

FASTA

>TPDB48943|Antifungal|length=63
EKLCTTIGDLDGKCSQDGEKLCMRYMTDQSKKKFLSCTCNNVVMLHKYKHYCECQSHCTPKQT

Formula C305H493N87O97S11

Absent Amino Acids AW

Common Amino Acids K

Mass 7283.45

PI 8.09

Basic Residues 13

Acidic Residues 7

Hydrophobic Residues 15

Net Charge +3

Boman Index 19.05

Hydrophobicity -0.768

Aliphatic Index 46.35

Half Life

Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour

Extinction Coefficient Cystines 4970

Absorbance 280nm 68.24

Polar Residues 27

number

0

A

1

R

2

N

4

D

8

C

3

E

4

Q

3

G

3

H

1

I

5

L

9

K

3

M

1

F

1

P

4

S

6

T

0

W

3

Y

2

V

Amino Acid Distribution

A: 0 R: 1 N: 2 D: 4 C: 8 E: 3 Q: 4 G: 3 H: 3 I: 1 L: 5 K: 9 M: 3 F: 1 P: 1 S: 4 T: 6 W: 0 Y: 3 V: 2

Length

63

Formula

C305H493N87O97S11

Mass

7283.45

PI

8.09

Net Charge

+3

Boman Index

19.05

Hydrophobicity

-0.768

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.