TPDB

3D PDB MODEL

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TPDB ID TPDB48939

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 96-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

SICNDRLGLCDGCDQRCKAKHGPSCESKCDGPVGMLLCTCTYECGPTKLCNGGLGNCGESCNEQCCDRNCAQRYNGGHGYCNTLDDFSLCLCKYPC

FASTA

>TPDB48939|Antifungal|length=96
SICNDRLGLCDGCDQRCKAKHGPSCESKCDGPVGMLLCTCTYECGPTKLCNGGLGNCGESCNEQCCDRNCAQRYNGGHGYCNTLDDFSLCLCKYPC

Formula C412H651N127O142S20

Absent Amino Acids W

Common Amino Acids C

Mass 10296.67

PI 5.42

Basic Residues 11

Acidic Residues 11

Hydrophobic Residues 19

Net Charge -3

Boman Index 19.32

Hydrophobicity -0.441

Aliphatic Index 45.73

Half Life

Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 7085

Absorbance 280nm 68.81

Polar Residues 42

number

2

A

4

R

7

N

7

D

19

C

4

E

3

Q

13

G

2

H

1

I

9

L

5

K

1

M

1

F

4

P

5

S

4

T

0

W

4

Y

1

V

Amino Acid Distribution

A: 2 R: 4 N: 7 D: 7 C: 19 E: 4 Q: 3 G: 13 H: 2 I: 1 L: 9 K: 5 M: 1 F: 1 P: 4 S: 5 T: 4 W: 0 Y: 4 V: 1

Length

96

Formula

C412H651N127O142S20

Mass

10296.67

PI

5.42

Net Charge

-3

Boman Index

19.32

Hydrophobicity

-0.441

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.