TPDB

3D PDB MODEL

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TPDB ID TPDB48933

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 74-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

HVREVKSVETKAKRVKKVCEKAQVFEQNCGWDGNKTCIRGFNKIKEYPFHCECGIYDAPNSRRICKCKFPYSPC

FASTA

>TPDB48933|Antifungal|length=74
HVREVKSVETKAKRVKKVCEKAQVFEQNCGWDGNKTCIRGFNKIKEYPFHCECGIYDAPNSRRICKCKFPYSPC

Formula C378H595N111O105S8

Absent Amino Acids LM

Common Amino Acids K

Mass 8631.04

PI 9.16

Basic Residues 18

Acidic Residues 8

Hydrophobic Residues 21

Net Charge +8

Boman Index 24.35

Hydrophobicity -0.778

Aliphatic Index 48.65

Half Life

Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour

Extinction Coefficient Cystines 10470

Absorbance 280nm 121.31

Polar Residues 22

number

3

A

5

R

4

N

2

D

8

C

6

E

2

Q

4

G

2

H

4

I

0

L

11

K

0

M

4

F

4

P

3

S

2

T

1

W

3

Y

6

V

Amino Acid Distribution

A: 3 R: 5 N: 4 D: 2 C: 8 E: 6 Q: 2 G: 4 H: 2 I: 4 L: 0 K: 11 M: 0 F: 4 P: 4 S: 3 T: 2 W: 1 Y: 3 V: 6

Length

74

Formula

C378H595N111O105S8

Mass

8631.04

PI

9.16

Net Charge

+8

Boman Index

24.35

Hydrophobicity

-0.778

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.