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Peptide record

TPDB48928

Antifungal standard
57 amino acids
Basic Information
3D PDB MODEL
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TPDB48928
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 57-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
KPRGKRPQSNFHAKRIRTVLQTLLVMLCTDYRCDKGLCKCHGFGGEKENPTAAPLTA
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C275H454N86O77S5
W
LK
6357.46
10.12
13
4
17
+7
2.13
-0.595
65.09
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1740
0.27
15
Residue Composition
number
4
A
5
R
2
N
2
D
4
C
2
E
2
Q
5
G
2
H
1
I
6
L
6
K
1
M
2
F
4
P
1
S
5
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 4 R: 5 N: 2 D: 2 C: 4 E: 2 Q: 2 G: 5 H: 2 I: 1 L: 6 K: 6 M: 1 F: 2 P: 4 S: 1 T: 5 W: 0 Y: 1 V: 2
Chemical Descriptors
57 reviewed residue count
C275H454N86O77S5 sequence-only estimate (linear, free termini)
6357.46 sequence-only estimate (linear, free termini)
10.12 sequence-only estimate (linear, free termini)
+7 sequence-only estimate (linear, free termini)
2.13 sequence-only estimate (linear, free termini)
-0.595 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.