TPDB

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

TPDB ID TPDB48927

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 54-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

QQQQQRCEEALTEIDCGAGNCNALCLQKRKGLGRCVQRTPCDKLKCMCYYPCSS

FASTA

>TPDB48927|Antifungal|length=54
QQQQQRCEEALTEIDCGAGNCNALCLQKRKGLGRCVQRTPCDKLKCMCYYPCSS

Formula C246H409N79O80S10

Absent Amino Acids HFW

Common Amino Acids C

Mass 6074.03

PI 8.02

Basic Residues 8

Acidic Residues 5

Hydrophobic Residues 13

Net Charge +3

Boman Index 14.28

Hydrophobicity -0.657

Aliphatic Index 54.26

Half Life

Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour

Extinction Coefficient Cystines 3480

Absorbance 280nm 57.29

Polar Residues 24

number

3

A

4

R

2

N

2

D

9

C

3

E

7

Q

4

G

0

H

1

I

5

L

4

K

1

M

0

F

2

P

2

S

2

T

0

W

2

Y

1

V

Amino Acid Distribution

A: 3 R: 4 N: 2 D: 2 C: 9 E: 3 Q: 7 G: 4 H: 0 I: 1 L: 5 K: 4 M: 1 F: 0 P: 2 S: 2 T: 2 W: 0 Y: 2 V: 1

Length

54

Formula

C246H409N79O80S10

Mass

6074.03

PI

8.02

Net Charge

+3

Boman Index

14.28

Hydrophobicity

-0.657

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.