TPDB

3D PDB MODEL

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TPDB ID TPDB48923

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 74-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

GLVRICNHRIEGYGTCGPNGRKICLDAFWKNQPSPGLSKNLEGCQCEDRRKRPQFKGLSHSCSCCWSYQGNSDE

FASTA

>TPDB48923|Antifungal|length=74
GLVRICNHRIEGYGTCGPNGRKICLDAFWKNQPSPGLSKNLEGCQCEDRRKRPQFKGLSHSCSCCWSYQGNSDE

Formula C351H548N112O108S8

Absent Amino Acids M

Common Amino Acids G

Mass 8321.38

PI 8.31

Basic Residues 13

Acidic Residues 7

Hydrophobic Residues 16

Net Charge +4

Boman Index 17.27

Hydrophobicity -0.885

Aliphatic Index 47.43

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 14480

Absorbance 280nm 174.01

Polar Residues 27

number

1

A

6

R

5

N

3

D

8

C

4

E

4

Q

9

G

2

H

3

I

5

L

5

K

0

M

2

F

4

P

7

S

1

T

2

W

2

Y

1

V

Amino Acid Distribution

A: 1 R: 6 N: 5 D: 3 C: 8 E: 4 Q: 4 G: 9 H: 2 I: 3 L: 5 K: 5 M: 0 F: 2 P: 4 S: 7 T: 1 W: 2 Y: 2 V: 1

Length

74

Formula

C351H548N112O108S8

Mass

8321.38

PI

8.31

Net Charge

+4

Boman Index

17.27

Hydrophobicity

-0.885

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.