TPDB

3D PDB MODEL

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TPDB ID TPDB48922

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 50-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

QETCHDLIMKRDCDEATCVNMCQQKWKGSGGSCFQNFNVMSCICNFPCQV

FASTA

>TPDB48922|Antifungal|length=50
QETCHDLIMKRDCDEATCVNMCQQKWKGSGGSCFQNFNVMSCICNFPCQV

Formula C234H364N68O75S11

Absent Amino Acids Y

Common Amino Acids C

Mass 5682.53

PI 5.41

Basic Residues 5

Acidic Residues 5

Hydrophobic Residues 14

Net Charge -1

Boman Index 9.21

Hydrophobicity -0.292

Aliphatic Index 42.80

Half Life

Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour

Extinction Coefficient Cystines 6000

Absorbance 280nm 105.59

Polar Residues 22

number

1

A

1

R

4

N

3

D

8

C

2

E

5

Q

3

G

1

H

2

I

1

L

3

K

3

M

3

F

1

P

3

S

2

T

1

W

0

Y

3

V

Amino Acid Distribution

A: 1 R: 1 N: 4 D: 3 C: 8 E: 2 Q: 5 G: 3 H: 1 I: 2 L: 1 K: 3 M: 3 F: 3 P: 1 S: 3 T: 2 W: 1 Y: 0 V: 3

Length

50

Formula

C234H364N68O75S11

Mass

5682.53

PI

5.41

Net Charge

-1

Boman Index

9.21

Hydrophobicity

-0.292

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.