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Peptide record

TPDB48919

Antifungal standard
52 amino acids
Basic Information
3D PDB MODEL
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TPDB48919
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 52-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
QTCFKGEAQEGVCVKVDGSKLCDLLCRATNTTWFGACEVEDNETHCHCYGPC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C238H365N67O80S8
IM
C
5701.40
4.58
6
8
14
-4
1.58
-0.298
50.58
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
7490
1.31
19
Residue Composition
number
3
A
1
R
2
N
3
D
8
C
5
E
2
Q
5
G
2
H
0
I
3
L
3
K
0
M
2
F
1
P
1
S
5
T
1
W
1
Y
4
V
Amino Acid Distribution
A: 3 R: 1 N: 2 D: 3 C: 8 E: 5 Q: 2 G: 5 H: 2 I: 0 L: 3 K: 3 M: 0 F: 2 P: 1 S: 1 T: 5 W: 1 Y: 1 V: 4
Chemical Descriptors
52 reviewed residue count
C238H365N67O80S8 sequence-only estimate (linear, free termini)
5701.40 sequence-only estimate (linear, free termini)
4.58 sequence-only estimate (linear, free termini)
-4 sequence-only estimate (linear, free termini)
1.58 sequence-only estimate (linear, free termini)
-0.298 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.