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Peptide record

TPDB48917

Antifungal standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB48917
Antifungal
Anti-infective peptides
AFP-GFuse
standard
No
A 15-aa standard natural antifungal peptide sequence curated from AFP-GFuse, with an available 3D structural model.
Sequence
RHCLRSKRPPNVCPH
Physicochemical Analysis
C75H126N30O18S2
ADEQGIMFTWY
RP
1800.14
11.23
6
0
2
+4
6.27
-1.327
45.33
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
125
6.94
4
Residue Composition
number
0
A
3
R
1
N
0
D
2
C
0
E
0
Q
0
G
2
H
0
I
1
L
1
K
0
M
0
F
3
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 2 I: 0 L: 1 K: 1 M: 0 F: 0 P: 3 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
15
C75H126N30O18S2
1800.14
11.23
+4
6.27
-1.327
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antifungal
1.56 µM

Target

B. subtilis

Source & Reference

NA

Other

active against B. subtilis (MIC 1.56 uM), S. aureus MRSA (MIC 6.25 uM), S. enterica (MIC 3.12 uM), P-aeruginosa (MIC> 50 uM), V-pa
Evidence 2 Activity

Activity

MIC
Antifungal
6.25 µM

Target

Staphylococcus aureus MRSA

Source & Reference

NA

Other

active against B. subtilis (MIC 1.56 uM), S. aureus MRSA (MIC 6.25 uM), S. enterica (MIC 3.12 uM), P-aeruginosa (MIC> 50 uM), V-parahaemolyticus (MIC > 50 uM),
Evidence 3 Activity

Activity

MIC
Antifungal
3.12 µM

Target

S. enterica

Source & Reference

NA

Other

active against B. subtilis (MIC 1.56 uM), S. aureus MRSA (MIC 6.25 uM), S. enterica (MIC 3.12 uM), P-aeruginosa (MIC> 50 uM), V-parahaemolyticus (MIC > 50 uM), and C. albicans (MIC 25 uM)
Evidence 4 Activity

Activity

MIC
Antifungal
25 µM

Target

Candida albicans

Source & Reference

NA

Other

enterica (MIC 3.12 uM), P-aeruginosa (MIC> 50 uM), V-parahaemolyticus (MIC > 50 uM), and C. albicans (MIC 25 uM).