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Peptide record

TPDB48912

Antifungal standard
48 amino acids
Basic Information
3D PDB MODEL
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TPDB48912
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 48-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
LDEPNMDTISKSREYKCKIDLDCSNHIACRHCSYRNCKCDHGTCKCMP
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C225H363N71O74S10
QFWV
C
5567.39
7.52
11
7
10
+1
2.92
-0.869
42.71
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
3480
0.63
19
Residue Composition
number
1
A
3
R
3
N
5
D
8
C
2
E
0
Q
1
G
3
H
3
I
2
L
5
K
2
M
0
F
2
P
4
S
2
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 1 R: 3 N: 3 D: 5 C: 8 E: 2 Q: 0 G: 1 H: 3 I: 3 L: 2 K: 5 M: 2 F: 0 P: 2 S: 4 T: 2 W: 0 Y: 2 V: 0
Chemical Descriptors
48 reviewed residue count
C225H363N71O74S10 sequence-only estimate (linear, free termini)
5567.39 sequence-only estimate (linear, free termini)
7.52 sequence-only estimate (linear, free termini)
+1 sequence-only estimate (linear, free termini)
2.92 sequence-only estimate (linear, free termini)
-0.869 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.