TPDB

3D PDB MODEL

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TPDB ID TPDB48898

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 55-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

NMGCMAVLGSCGVITDCSGECISRFGPQARGYCDRDGGSGTCVCVYPCPADKPHM

FASTA

>TPDB48898|Antifungal|length=55
NMGCMAVLGSCGVITDCSGECISRFGPQARGYCDRDGGSGTCVCVYPCPADKPHM

Formula C231H365N69O76S11

Absent Amino Acids W

Common Amino Acids G

Mass 5677.52

PI 5.36

Basic Residues 5

Acidic Residues 5

Hydrophobic Residues 16

Net Charge -1

Boman Index 7.98

Hydrophobicity 0.022

Aliphatic Index 47.82

Half Life

Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour

Extinction Coefficient Cystines 3480

Absorbance 280nm 61.29

Polar Residues 18

number

3

A

3

R

1

N

4

D

8

C

1

E

1

Q

9

G

1

H

2

I

1

L

1

K

3

M

1

F

4

P

4

S

2

T

0

W

2

Y

4

V

Amino Acid Distribution

A: 3 R: 3 N: 1 D: 4 C: 8 E: 1 Q: 1 G: 9 H: 1 I: 2 L: 1 K: 1 M: 3 F: 1 P: 4 S: 4 T: 2 W: 0 Y: 2 V: 4

Length

55

Formula

C231H365N69O76S11

Mass

5677.52

PI

5.36

Net Charge

-1

Boman Index

7.98

Hydrophobicity

0.022

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.