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Peptide record

TPDB48894

Antifungal standard
65 amino acids
Basic Information
3D PDB MODEL
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TPDB48894
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 65-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
KTKWGCDMNRPFPGKCGTNGKDTCISDIKKMPGAPKDLVVRCECSQRFVWKGYPPERLCKCQYDC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C320H506N92O91S10
H
K
7418.70
8.72
13
7
16
+6
2.17
-0.789
38.92
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
14480
1.95
19
Residue Composition
number
1
A
4
R
2
N
5
D
8
C
2
E
2
Q
6
G
0
H
2
I
2
L
9
K
2
M
2
F
6
P
2
S
3
T
2
W
2
Y
3
V
Amino Acid Distribution
A: 1 R: 4 N: 2 D: 5 C: 8 E: 2 Q: 2 G: 6 H: 0 I: 2 L: 2 K: 9 M: 2 F: 2 P: 6 S: 2 T: 3 W: 2 Y: 2 V: 3
Chemical Descriptors
65 reviewed residue count
C320H506N92O91S10 sequence-only estimate (linear, free termini)
7418.70 sequence-only estimate (linear, free termini)
8.72 sequence-only estimate (linear, free termini)
+6 sequence-only estimate (linear, free termini)
2.17 sequence-only estimate (linear, free termini)
-0.789 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.