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Peptide record

TPDB48892

Antifungal standard
73 amino acids
Basic Information
3D PDB MODEL
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TPDB48892
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 73-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
EESRMNINAERRPWCPSKIQMFDTNCEVDGAKQCLDLLISTWDPSVRLTRVSCICSDFPYRNMMCSCPNMICP
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C356H566N102O110S13
H
C
8451.81
4.97
8
9
24
-1
2.11
-0.310
62.74
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
12990
1.54
26
Residue Composition
number
2
A
6
R
5
N
5
D
8
C
4
E
2
Q
1
G
0
H
5
I
4
L
2
K
5
M
2
F
6
P
7
S
3
T
2
W
1
Y
3
V
Amino Acid Distribution
A: 2 R: 6 N: 5 D: 5 C: 8 E: 4 Q: 2 G: 1 H: 0 I: 5 L: 4 K: 2 M: 5 F: 2 P: 6 S: 7 T: 3 W: 2 Y: 1 V: 3
Chemical Descriptors
73 reviewed residue count
C356H566N102O110S13 sequence-only estimate (linear, free termini)
8451.81 sequence-only estimate (linear, free termini)
4.97 sequence-only estimate (linear, free termini)
-1 sequence-only estimate (linear, free termini)
2.11 sequence-only estimate (linear, free termini)
-0.310 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.